BindingDB logo
myBDB logout

BDBM50321995 5-(2-Chlorophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1173602

SMILES: NC(=S)N1N=C(CC1c1ccccc1Cl)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=USJAOUSWGAHVII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321995   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50321995
PNG
(5-(2-Chlorophenyl)-3-(3,4-dichlorophenyl)-4,5-dihy...)
Show SMILES NC(=S)N1N=C(CC1c1ccccc1Cl)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C16H12Cl3N3S/c17-11-4-2-1-3-10(11)15-8-14(21-22(15)16(20)23)9-5-6-12(18)13(19)7-9/h1-7,15H,8H2,(H2,20,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.28E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of histidine-tagged recombinant EGFR autophosphorylation expressed in Sf9 cells by solid-phase ELISA


Bioorg Med Chem 18: 4606-14 (2011)


Article DOI: 10.1016/j.bmc.2010.05.034
BindingDB Entry DOI: 10.7270/Q22R3SMJ
More data for this
Ligand-Target Pair