BindingDB logo
myBDB logout

BDBM50322000 3-(3,4-Dichlorophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1172916

SMILES: Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=HYKGIFCAVSPOCM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322000   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (human))
BDBM50322000
PNG
(3-(3,4-Dichlorophenyl)-5-p-tolyl-4,5-dihydro-1H-py...)
Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H15Cl2N3S/c1-10-2-4-11(5-3-10)16-9-15(21-22(16)17(20)23)12-6-7-13(18)14(19)8-12/h2-8,16H,9H2,1H3,(H2,20,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.38E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of histidine-tagged recombinant EGFR autophosphorylation expressed in Sf9 cells by solid-phase ELISA


Bioorg Med Chem 18: 4606-14 (2011)


Article DOI: 10.1016/j.bmc.2010.05.034
BindingDB Entry DOI: 10.7270/Q22R3SMJ
More data for this
Ligand-Target Pair