BDBM50322111 CHEMBL1170672::N-Cyclopentyl-3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine

SMILES O=S(=O)(c1nnn2c3ccsc3c(NC3CCCC3)nc12)c1ccccc1

InChI Key InChIKey=GVDQFVNVDQGADB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322111   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322111(CHEMBL1170672 | N-Cyclopentyl-3-(phenylsulfonyl)th...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322111(CHEMBL1170672 | N-Cyclopentyl-3-(phenylsulfonyl)th...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322111(CHEMBL1170672 | N-Cyclopentyl-3-(phenylsulfonyl)th...)
Affinity DataIC50:  11.9nMAssay Description:Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed