BDBM50322940 2-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-N-(3-(trifluoromethyl)phenyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210629

SMILES Fc1ccc(cc1F)N1C(c2ccccn2)C2(CCN(CC2)C(=O)Nc2cccc(c2)C(F)(F)F)C1=O

InChI Key InChIKey=BPHWNJKVRYIGRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322940   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322940(2-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-N-(3...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322940(2-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-N-(3...)
Affinity DataIC50:  283nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322940(2-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-N-(3...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed