BDBM50323027 (1S,2S,6R,7R)-4-(4-Cyano-3-trifluoromethyl-phenyl)-1,7-dimethyl-3,5-dioxo-11-oxa-4,9-diaza-tricyclo[5.3.1.0*2,6*]undecane-9-carboxylic acid isopropylamide::CHEMBL1209971

SMILES CC(C)NC(=O)N1C[C@]2(C)O[C@](C)(C1)c1c(O)n(c(O)c21)-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=GAJPZXUFNIIEEO-OYRHEFFESA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323027   

TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323027((1S,2S,6R,7R)-4-(4-Cyano-3-trifluoromethyl-phenyl)...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]DHT from AR in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323027((1S,2S,6R,7R)-4-(4-Cyano-3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  876nMAssay Description:Antagonist activity at human wild type AR expressed in human MDA-MB-435 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323027((1S,2S,6R,7R)-4-(4-Cyano-3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  4.60E+3nMAssay Description:Antagonist activity at wild type human AR expressed in human LNCAP cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed