BDBM50323204 7'',4'''-dimethylamentoflavone::CHEMBL374055

SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1

InChI Key InChIKey=DQIHYHXGJITSCH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323204   

TargetBeta-secretase 1(Human)
Shujitsu University

Curated by ChEMBL
LigandPNGBDBM50323204(7'',4'''-dimethylamentoflavone | CHEMBL374055)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50323204(7'',4'''-dimethylamentoflavone | CHEMBL374055)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50323204(7'',4'''-dimethylamentoflavone | CHEMBL374055)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed