BDBM50323544 4-(1-(6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)ethoxy)benzoic acid::CHEMBL1209365
SMILES CC(Oc1ccc(cc1)C(O)=O)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)nc1C(F)(F)F
InChI Key InChIKey=KQLXPIYHRHYSJY-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50323544
Affinity DataEC50: 189nMAssay Description:Agonist activity at human GST-fused FXR LBD expressed in HEK293 cells coexpressing GAL4-DNA bindig domain and pFRluc by mammalian one-hybrid assayMore data for this Ligand-Target Pair
Affinity DataEC50: 611nMAssay Description:Agonist activity at human full length FXR transfected in HEK293 cells coexpressing pTRexDest/pGL2promotor assessed as luciferase activity by direct r...More data for this Ligand-Target Pair
Affinity DataEC50: 352nMAssay Description:Agonist activity at human GST-fused FXR LBD assessed as cofactor peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair