BDBM50323710 (1R,2R,3S,4R,6S)-3,6-dihydroxycyclohexane-1,2,4-triyl triphosphate::CHEMBL1213201

SMILES O[C@H]1C[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O

InChI Key InChIKey=GHYKQXTYUPPQMF-DSOBHZJASA-N

Data  3 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323710   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323710((1R,2R,3S,4R,6S)-3,6-dihydroxycyclohexane-1,2,4-tr...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at rat recombinant IP3R1 expressed in chicken DT40 cells assessed as calcium release from intracellular storesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323710((1R,2R,3S,4R,6S)-3,6-dihydroxycyclohexane-1,2,4-tr...)
Affinity DataKd:  0.220nMAssay Description:Displacement of [3H]IP3 from rat recombinant IP3R1 binding core residue (224-604) expressed in chicken DT40 cells by equilibrium competitive binding ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323710((1R,2R,3S,4R,6S)-3,6-dihydroxycyclohexane-1,2,4-tr...)
Affinity DataKd:  4.01nMAssay Description:Displacement of [3H]IP3 from rat recombinant N-terminal IP3R1 (1-604) expressed in chicken DT40 cells by equilibrium competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323710((1R,2R,3S,4R,6S)-3,6-dihydroxycyclohexane-1,2,4-tr...)
Affinity DataKd:  17.1nMAssay Description:Displacement of [3H]IP3 from full-length rat recombinant IP3R1 expressed in chicken DT40 cells by equilibrium competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed