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BDBM50323901 CHEMBL1213846::E-2-(2-(3-(4-(4-(4-Chlorophenoxy)butoxy)phenyl)acryloyl)phenoxy)acetic acid

SMILES: OC(=O)COc1ccccc1C(=O)\C=C\c1ccc(OCCCCOc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=SFEWGPHCEYARMN-CXUHLZMHSA-N

Data: 1 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323901   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteinyl leukotriene receptor


(HUMAN)
BDBM50323901
PNG
(CHEMBL1213846 | E-2-(2-(3-(4-(4-(4-Chlorophenoxy)b...)
Show SMILES OC(=O)COc1ccccc1C(=O)\C=C\c1ccc(OCCCCOc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C27H25ClO6/c28-21-10-14-23(15-11-21)33-18-4-3-17-32-22-12-7-20(8-13-22)9-16-25(29)24-5-1-2-6-26(24)34-19-27(30)31/h1-2,5-16H,3-4,17-19H2,(H,30,31)/b16-9+
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Similars

Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...


Bioorg Med Chem 18: 5519-27 (2010)


Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0
More data for this
Ligand-Target Pair