BDBM50324086 CHEMBL1214893::N-(Benzofuran-2-ylmethyl)-N'-(4'-(3''-fluoropropoxy)benzyl)-piperazine

SMILES FCCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1

InChI Key InChIKey=SPOINIWQULRMHV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324086   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324086(CHEMBL1214893 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...)
Affinity DataKi:  1.61nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324086(CHEMBL1214893 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...)
Affinity DataKi:  14.7nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324086(CHEMBL1214893 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...)
Affinity DataKi:  232nMAssay Description:Binding affinity to 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324086(CHEMBL1214893 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...)
Affinity DataKi:  3.30E+3nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324086(CHEMBL1214893 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed