BDBM50324097 CHEMBL1214831::N-(Benzofuran-2-ylmethyl)-N'-(4'-ethoxybenzyl)piperazine

SMILES CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1

InChI Key InChIKey=SARQYPUTTRFHLZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324097   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324097(CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324097(CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...)
Affinity DataKi:  10.6nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324097(CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...)
Affinity DataKi:  262nMAssay Description:Binding affinity to 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324097(CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...)
Affinity DataKi:  3.34E+3nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324097(CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...)
Affinity DataKi:  4.87E+3nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed