BDBM50324333 2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-yl[2,4']bipyridinyl-4-carbonitrile::CHEMBL1215150

SMILES Cn1ccc(Nc2cc(ccn2)-c2cc(cc(n2)N2CCNCC2)C#N)n1

InChI Key InChIKey=ZVKJUDYDWABBFR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324333   

TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324333(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324333(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50:  68nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324333(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataEC50:  428nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed