BDBM50324509 CHEMBL1215373::N-(2-(1H-imidazol-4-yl)ethyl)-6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamide

SMILES Cc1nc2nc(cn2c(c1CN)-c1ccc(Cl)cc1Cl)C(=O)NCCc1cnc[nH]1

InChI Key InChIKey=BXRCSZPNYWMUNQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324509   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324509(CHEMBL1215373 | N-(2-(1H-imidazol-4-yl)ethyl)-6-(a...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324509(CHEMBL1215373 | N-(2-(1H-imidazol-4-yl)ethyl)-6-(a...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324509(CHEMBL1215373 | N-(2-(1H-imidazol-4-yl)ethyl)-6-(a...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed