BDBM50324922 (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(cyclohexylmethyl)pentanamide::(S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclohexylmethyl)pentanamide::CHEMBL1222240

SMILES CC[C@@H](CC(=O)NCC1CCCCC1)n1c(N)nc2cc(Cl)ccc12

InChI Key InChIKey=UKACQFCXAAAWAE-HNNXBMFYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324922   

TargetBeta-secretase 1(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed