BDBM50324935 (R)-2-((S)-4-(2-(5-fluoro-1H-indol-3-yl)ethylamino)-2-isopropyl-4-oxobutanamido)-3-oxopropanoic acid::CHEMBL1221599

SMILES CC(C)[C@H](CC(=O)NCCc1c[nH]c2ccc(F)cc12)C(=O)N[C@@H](CC(O)=O)C=O

InChI Key InChIKey=VGFJRCPXGNOGEI-HOTGVXAUSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324935   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324935((R)-2-((S)-4-(2-(5-fluoro-1H-indol-3-yl)ethylamino...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324935((R)-2-((S)-4-(2-(5-fluoro-1H-indol-3-yl)ethylamino...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed