BDBM50324952 (R)-2-((S)-2-isopropyl-4-(2-(2-methyl-1H-indol-3-yl)ethylamino)-4-oxobutanamido)-3-oxopropanoic acid::CHEMBL1221643

SMILES CC(C)[C@H](CC(=O)NCCc1c(C)[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C=O

InChI Key InChIKey=RFONTQSPUOYGCX-YJBOKZPZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324952   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324952((R)-2-((S)-2-isopropyl-4-(2-(2-methyl-1H-indol-3-y...)
Affinity DataKi:  1.29nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324952((R)-2-((S)-2-isopropyl-4-(2-(2-methyl-1H-indol-3-y...)
Affinity DataKi:  13.4nMAssay Description:Inhibition of mouse ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324952((R)-2-((S)-2-isopropyl-4-(2-(2-methyl-1H-indol-3-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed