BDBM50324958 (S)-3-((S)-2-isopropyl-4-(2-(2-methyl-1H-benzo[d]imidazol-1-yl)ethylamino)-4-oxobutanamido)-4-oxobutanoic acid::CHEMBL1221689

SMILES CC(C)[C@H](CC(=O)NCCn1c(C)nc2ccccc12)C(=O)N[C@@H](CC(O)=O)C=O

InChI Key InChIKey=MJSGCNFYDWNMSU-HOTGVXAUSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324958   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324958((S)-3-((S)-2-isopropyl-4-(2-(2-methyl-1H-benzo[d]i...)
Affinity DataKi:  4.68nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324958((S)-3-((S)-2-isopropyl-4-(2-(2-methyl-1H-benzo[d]i...)
Affinity DataKi:  18.7nMAssay Description:Inhibition of mouse ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324958((S)-3-((S)-2-isopropyl-4-(2-(2-methyl-1H-benzo[d]i...)
Affinity DataIC50:  23.8nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed