BDBM50325541 CHEMBL1224483::CHEMBL1229058::S-(2,4-Dichlorobenzyl)isothiourea hydrobromide::cid_15945669

SMILES NC(=N)SCc1ccc(Cl)cc1Cl

InChI Key InChIKey=KTXXYZBSQYXMPO-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325541   

TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50325541(CHEMBL1224483 | CHEMBL1229058 | S-(2,4-Dichloroben...)
Affinity DataEC50: <195nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325541(CHEMBL1224483 | CHEMBL1229058 | S-(2,4-Dichloroben...)
Affinity DataIC50:  400nMAssay Description:Inhibition of indoleamine-2,3-dioxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325541(CHEMBL1224483 | CHEMBL1229058 | S-(2,4-Dichloroben...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of indoleamine-2,3-dioxygenase in human A431 cells assessed as inhibition of IFN-gamma-stimulated kynurenine productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325541(CHEMBL1224483 | CHEMBL1229058 | S-(2,4-Dichloroben...)
Affinity DataIC50:  400nMAssay Description:Inhibition of IDO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed