BDBM50325662 CHEMBL1224034::N-cyclohexyl-8-fluoro-3,3a,4,9b-tetrahydro-1H-thiochromeno[4,3-c]isoxazole-1-carboxamide

SMILES Fc1ccc2SCC3CON(C3c2c1)C(=O)NC1CCCCC1

InChI Key InChIKey=WPNGDOZEXVRNMZ-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50325662   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Mesulergine from human 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN-3542 from human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Citalopram from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Nisoxetine from human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human 5HT2B receptor assessed as 10633-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Csiro Molecular And Health Technologies

Curated by ChEMBL
LigandPNGBDBM50325662(CHEMBL1224034 | N-cyclohexyl-8-fluoro-3,3a,4,9b-te...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human 5HT2C receptor assessed as 10633-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed