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BDBM50325824 1H-purine-2,6,8(3H,7H,9H)-trione::7,9-Dihydro-3H-purine-2,6,8-trione::7,9-Dihydro-3H-purine-2,6,8-trione(Urate)::7,9-Dihydro-3H-purine-2,6,8-trione(uric acid)::CHEMBL792::URIC ACID

SMILES: O=c1[nH]c2[nH]c(=O)[nH]c(=O)c2[nH]1

InChI Key: InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N

Data: 2 KI

PDB links: 17 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325824   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Guanine deaminase


(Homo sapiens)
BDBM50325824
PNG
(1H-purine-2,6,8(3H,7H,9H)-trione | 7,9-Dihydro-3H-...)
Show SMILES O=c1[nH]c2[nH]c(=O)[nH]c(=O)c2[nH]1
Show InChI InChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
PDB
MMDB

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KEGG

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KEGG
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PC cid
PC sid
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Similars

Article
PubMed
4.34E+3n/an/an/an/an/an/an/an/a



The State University of New Jersey

Curated by ChEMBL


Assay Description
Inhibition of GDA by colorimetric assay


Bioorg Med Chem 18: 6748-55 (2010)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 8


(Homo sapiens)
BDBM50325824
PNG
(1H-purine-2,6,8(3H,7H,9H)-trione | 7,9-Dihydro-3H-...)
Show SMILES O=c1[nH]c2[nH]c(=O)[nH]c(=O)c2[nH]1
Show InChI InChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
2.75E+5n/an/an/an/an/an/an/an/a



Georg-August-Universit£t

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate in Xenopus laevis oocytes


Cell Physiol Biochem 13: 249-56 (2003)

More data for this
Ligand-Target Pair