BDBM50325954 CHEMBL1223884::N-(3-(1-(3-(1-(4-tert-butylbenzyl)-1H-benzo[d]imidazol-2-ylamino)propyl)piperidin-4-yl)phenyl)acetamide

SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCNc2nc3ccccc3n2Cc2ccc(cc2)C(C)(C)C)CC1

InChI Key InChIKey=GOUXVFGHGYYLAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325954   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325954(CHEMBL1223884 | N-(3-(1-(3-(1-(4-tert-butylbenzyl)...)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHOK1 cells assessed as reduction in [3H]inositol phosphate levels by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325954(CHEMBL1223884 | N-(3-(1-(3-(1-(4-tert-butylbenzyl)...)
Affinity DataIC50:  320nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHOK1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed