BDBM50326423 3-(4-fluorophenyl)-N-methylimidazo[1,2-b]pyridazin-6-amine::CHEMBL1240535::US10688093, Compound 437_0339::US11701353, Compound 437_0339

SMILES CNc1ccc2ncc(-c3ccc(F)cc3)n2n1

InChI Key InChIKey=ZVPZLFAIHCCXLL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326423   

TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50326423(3-(4-fluorophenyl)-N-methylimidazo[1,2-b]pyridazin...)
Affinity DataIC50:  3.26E+3nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50326423(3-(4-fluorophenyl)-N-methylimidazo[1,2-b]pyridazin...)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed