BDBM50326669 17-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL606771

SMILES CN1CC[C@]23[C@H]4Oc5cccc(C[C@@H]1[C@]2(O)CCC4=O)c35

InChI Key InChIKey=FZMIRDYCNXDMGZ-BSWAZPDLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326669   

LigandPNGBDBM50326669(17-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyc...)
Affinity DataIC50:  1.40nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi

Curated by ChEMBL
LigandPNGBDBM50326669(17-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyc...)
Affinity DataIC50:  6.53E+4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50326669(17-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyc...)
Affinity DataIC50:  16nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the presence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed