BindingDB logo
myBDB logout

BDBM50326775 CHEMBL1254537::N,1-Bis(3-chlorophenyl)-4-methyl-5-methylene-2-oxo-N-phenyl-2,5-dihydro-1H-pyrrole-3-carboxamide

SMILES: CC1=C(C(=O)Nc2cccc(Cl)c2)C(=O)N(C1=C)c1cccc(Cl)c1

InChI Key: InChIKey=XDDAYQPNDDSZMV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326775   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ecdysone receptor


(Lucilia cuprina)
BDBM50326775
PNG
(CHEMBL1254537 | N,1-Bis(3-chlorophenyl)-4-methyl-5...)
Show SMILES CC1=C(C(=O)Nc2cccc(Cl)c2)C(=O)N(C1=C)c1cccc(Cl)c1
Show InChI InChI=1S/C19H14Cl2N2O2/c1-11-12(2)23(16-8-4-6-14(21)10-16)19(25)17(11)18(24)22-15-7-3-5-13(20)9-15/h3-10H,2H2,1H3,(H,22,24)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.50E+5n/an/an/an/an/an/a



CSIRO Molecular and Health Technologies

Curated by ChEMBL


Assay Description
Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assay


Bioorg Med Chem 18: 5647-60 (2010)


Article DOI: 10.1016/j.bmc.2010.06.020
BindingDB Entry DOI: 10.7270/Q2MK6D43
More data for this
Ligand-Target Pair