BDBM50326781 (S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamino)hexan-2-ylcarbamate::CHEMBL1254035

SMILES CC(=[Se])NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1

InChI Key InChIKey=VTIURJZGHKSCOK-FQEVSTJZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326781   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50326781((S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamin...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-SIRT1 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50326781((S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamin...)
Affinity DataIC50:  2.85E+5nMAssay Description:Inhibition of human recombinant SIRT6 assessed as 7-amino-4-methylcoumarin labelled Arg-His-Lys-Lys(epsilon-acetyl) substrate deacetylation after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50326781((S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamin...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GST-SIRT2 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed