BDBM50326989 3-((Z)-4-(((R)-2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)but-2-enyl)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one::CHEMBL1253992
SMILES COc1ccc(cc1OC)[C@@H](C)CN(C)C\C=C/CN1C=Cc2cc(OC)c(OC)cc2CC1=O
InChI Key InChIKey=KAZRQWNQMDRZLD-AQWUKCDYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50326989
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 9.41E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.49E+4nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair