BDBM50327259 3-(1-benzylpiperidin-4-yloxy)benzamide::CHEMBL1257457

SMILES NC(=O)c1cccc(OC2CCN(Cc3ccccc3)CC2)c1

InChI Key InChIKey=IDSIUINGWBNUFD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327259   

TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327259(3-(1-benzylpiperidin-4-yloxy)benzamide | CHEMBL125...)
Affinity DataKi:  75nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327259(3-(1-benzylpiperidin-4-yloxy)benzamide | CHEMBL125...)
Affinity DataIC50:  585nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327259(3-(1-benzylpiperidin-4-yloxy)benzamide | CHEMBL125...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human mu opioid receptor assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327259(3-(1-benzylpiperidin-4-yloxy)benzamide | CHEMBL125...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human delta opioid receptor assessed as inhibition of SNC80-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed