BDBM50327289 CHEMBL1257940::methyl 2-(4'-(1-amino-3-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)propan-2-yl)-3'-methylbiphenyl-2-yl)acetate

SMILES COC(=O)Cc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1

InChI Key InChIKey=COEFPCKSMNXHEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327289   

TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327289(CHEMBL1257940 | methyl 2-(4'-(1-amino-3-(4-(2-(2,6...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant renin in phosphate bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327289(CHEMBL1257940 | methyl 2-(4'-(1-amino-3-(4-(2-(2,6...)
Affinity DataIC50:  534nMAssay Description:Inhibition of human recombinant renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed