BDBM50327609 7-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)isoindolin-1-one::CHEMBL1257969

SMILES Fc1c2C(=O)NCc2ccc1OCCCN1CCN(CC1)c1cccc2ccccc12

InChI Key InChIKey=QCTMCGZINYAROF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327609   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327609(7-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.128nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327609(7-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  2.21nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327609(7-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  13.8nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327609(7-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  84.7nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed