BDBM50328809 CHEMBL1270165::rac-1,2,5-trimethyl-4-(2-(naphthalen-2-yl)ethyl)piperidin-4-ol

SMILES CC1CC(O)(CCc2ccc3ccccc3c2)C(C)CN1C

InChI Key InChIKey=ICKWJAMESDNKEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328809   

TargetHistamine H3 receptor(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50328809(CHEMBL1270165 | rac-1,2,5-trimethyl-4-(2-(naphthal...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity against human histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Athersys

Curated by ChEMBL
LigandPNGBDBM50328809(CHEMBL1270165 | rac-1,2,5-trimethyl-4-(2-(naphthal...)
Affinity DataIC50:  122nMAssay Description:Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed