BDBM50328883 3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)-N-(pentan-3-yl)propanamide::CHEMBL1271275

SMILES CCC(CC)NC(=O)CCc1cc(nc(n1)C#N)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=WSXMUOJNQNRRSA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328883   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328883(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimidin-...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H] dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328883(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimidin-...)
Affinity DataIC50:  389nMAssay Description:Inhibition of human recombinant cathepsin K using Z-Phe-Arg-MCA substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed