BDBM50329773 (-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol::CHEMBL1271793

SMILES O[C@@H]1Cc2cccc(OCCF)c2C[C@H]1N1CCC(CC1)c1ccccc1

InChI Key InChIKey=QDERQSYUBLZZNW-FGZHOGPDSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329773   

TargetVesicular acetylcholine transporter(Rattus norvegicus)
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50329773((-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidi...)
Affinity DataKi:  19.6nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVesicular acetylcholine transporter(Rattus norvegicus)
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50329773((-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidi...)
Affinity DataKi:  20nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50329773((-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidi...)
Affinity DataKi:  209nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat cortical membranes after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50329773((-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidi...)
Affinity DataKi:  209nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed