BDBM50329791 (Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfonamido)phenylamino)(phenyl)methylene)-N-ethyl-2-oxoindoline-6-carboxamide::CHEMBL1272128

SMILES CCNC(=O)c1ccc2C(C(=Nc3ccc(cc3)N(CCN(C)C)S(C)(=O)=O)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=FGCSLJAOHVQQFY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329791   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329791((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataIC50:  1nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329791((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataIC50:  74nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329791((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataEC50:  108nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed