BDBM50329879 5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)pyridin-2(1H)-one::CHEMBL1271480

SMILES O=c1ccc(c[nH]1)-c1cnn2cc(cnc12)-c1ccc(OCCN2CCOCC2)cc1

InChI Key InChIKey=WMXDIPVFXWNELM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50329879   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  61nMAssay Description:Inhibition of c-SRC by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  260nMAssay Description:Inhibition of EphA2 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  470nMAssay Description:Inhibition of FLT1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of RSK1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  430nMAssay Description:Inhibition of LCK by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MNK1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329879(5-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50:  100nMAssay Description:Inhibition of KDR by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed