BDBM50330104 CHEMBL1271658::N-(6-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-3-yl)benzamide

SMILES FC(F)(F)c1cc(nn1-c1ccc(NC(=O)c2ccccc2)cn1)-c1cccnc1

InChI Key InChIKey=YOXPNAZATYYXDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330104   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330104(CHEMBL1271658 | N-(6-(3-(pyridin-3-yl)-5-(trifluor...)
Affinity DataIC50:  397nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330104(CHEMBL1271658 | N-(6-(3-(pyridin-3-yl)-5-(trifluor...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed