BDBM50330241 (E)-4-(Dimethylamino)-1-(4-[(1R)-1-phenylethyl]amino-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl)-2-buten-1-one::CHEMBL1271561::US8524722, 23
SMILES C[C@@H](Nc1ncnc2sc3CN(CCc3c12)C(=O)\C=C\CN(C)C)c1ccccc1
InChI Key InChIKey=BVGZQNBERZRYJK-OJXHRBAXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50330241
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 4.60nMpH: 7.0 T: 2°CAssay Description:EGFR inhibitory activity of compounds of the present invention is quantified employing the EGFR HTRF assay.More data for this Ligand-Target Pair