BDBM50330338 CHEMBL1276017::Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl)phenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate

SMILES [#6]-[#6]-[#8]-[#6](=O)-c1c(nn(c1-c1ccccc1)-c1cccc(-[#7]\[#7]=[#6](/[#6](-[#6])=O)-[#6](-[#6])=O)c1)-[#6](=O)-[#7]-c1nnc(s1)S([#7])(=O)=O

InChI Key InChIKey=KYWMOFHTUPLELW-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50330338   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(CHEMBL1276017 | Ethyl1-(3-(2-(2,4-dioxopentan-3-yl...)
Affinity DataKi:  170nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(CHEMBL1276017 | Ethyl1-(3-(2-(2,4-dioxopentan-3-yl...)
Affinity DataKi:  250nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(CHEMBL1276017 | Ethyl1-(3-(2-(2,4-dioxopentan-3-yl...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(CHEMBL1276017 | Ethyl1-(3-(2-(2,4-dioxopentan-3-yl...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(CHEMBL1276017 | Ethyl1-(3-(2-(2,4-dioxopentan-3-yl...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(CHEMBL1276017 | Ethyl1-(3-(2-(2,4-dioxopentan-3-yl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed