BDBM50330746 2-(2-chlorophenyl)-4-(2-fluorophenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1278018

SMILES Cn1c(-c2ccccc2F)c2c(cc1=O)[nH]n(-c1ccccc1Cl)c2=O

InChI Key InChIKey=KJQWOWLDTVSADY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330746   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330746(2-(2-chlorophenyl)-4-(2-fluorophenyl)-5-methyl-1H-...)
Affinity DataKi:  128nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed