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BDBM50330859 10-Hydroxy-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide::10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide::10-hydroxy-carbamazepine::CHEMBL1067::Licarbazepine

SMILES: NC(=O)N1c2ccccc2CC(O)c2ccccc12

InChI Key: InChIKey=BMPDWHIDQYTSHX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330859   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor (2b and 2c)


(Homo sapiens (human))
BDBM50330859
PNG
(10-Hydroxy-10,11-dihydro-dibenzo[b,f]azepine-5-car...)
Show SMILES NC(=O)N1c2ccccc2CC(O)c2ccccc12
Show InChI InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
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KEGG

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CHEMBL
KEGG
PC cid
PC sid
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Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation counting


J Med Chem 53: 7573-86 (2010)

More data for this
Ligand-Target Pair
P2X purinoceptor 4


(HUMAN)
BDBM50330859
PNG
(10-Hydroxy-10,11-dihydro-dibenzo[b,f]azepine-5-car...)
Show SMILES NC(=O)N1c2ccccc2CC(O)c2ccccc12
Show InChI InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...


Bioorg Med Chem 22: 1077-88 (2014)

More data for this
Ligand-Target Pair