BDBM50330873 CHEMBL1277786::US9090589, 4::trans rac-N1-(4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)-N2-phenethylethane-1,2-diamine
SMILES Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCCc2ccccc2)c1
InChI Key InChIKey=OOOHDCHGOXCPHM-ICSRJNTNSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50330873
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 1.24E+5nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+5nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair