BDBM50331363 (S)-3'-cyclopropyl-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile::CHEMBL1289521

SMILES C[C@](O)(c1ccc(cc1)S(=O)(=O)c1ccc(cc1C1CC1)-c1ccc(cc1)C#N)C(F)(F)F

InChI Key InChIKey=ZHGJYPFTAUOXEU-DEOSSOPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331363   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50331363((S)-3'-cyclopropyl-4'-(4-(1,1,1-trifluoro-2-hydrox...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50331363((S)-3'-cyclopropyl-4'-(4-(1,1,1-trifluoro-2-hydrox...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed