BDBM50331723 CHEMBL1290637::N-(2-oxo-2-((3S,4S)-1-(cis-4-phenylcyclohexyl)-4-propoxypyrrolidin-3-ylamino)ethyl)-3-(trifluoromethyl)benzamide
SMILES CCCO[C@H]1CN(C[C@@H]1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)[C@H]1CC[C@H](CC1)c1ccccc1
InChI Key InChIKey=SQAGKRMXWWHHJT-QUKDMSEQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50331723
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair