BDBM50331897 CHEMBL1289107::E-5-Fluoro-3-[[4-(methylsulfonyl)phenyl]methylene]-indolin-2-one
SMILES CS(=O)(=O)c1ccc(\C=C2\C(=O)Nc3ccc(F)cc23)cc1
InChI Key InChIKey=CCFTYTAWQLACEE-RIYZIHGNSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50331897
TargetProstaglandin G/H synthase 2(Oryctolagus cuniculus)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Oryctolagus cuniculus)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.99E+3nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair