BDBM50331897 CHEMBL1289107::E-5-Fluoro-3-[[4-(methylsulfonyl)phenyl]methylene]-indolin-2-one

SMILES CS(=O)(=O)c1ccc(\C=C2\C(=O)Nc3ccc(F)cc23)cc1

InChI Key InChIKey=CCFTYTAWQLACEE-RIYZIHGNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331897   

TargetProstaglandin G/H synthase 2(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331897(CHEMBL1289107 | E-5-Fluoro-3-[[4-(methylsulfonyl)p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331897(CHEMBL1289107 | E-5-Fluoro-3-[[4-(methylsulfonyl)p...)
Affinity DataIC50:  8.99E+3nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed