BDBM50332020 CHEMBL1289468::N-(3-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)benzenesulfonamide
SMILES COc1ccc(cc1OC)-c1c[nH]c2ncc(cc12)-c1cccc(NS(=O)(=O)c2ccccc2)c1
InChI Key InChIKey=CZLHISAYBVESEH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50332020
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of c-KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of c-KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataKd: 2.30E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Advanced Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataKd: 91nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair