BDBM50332040 CHEMBL1288895::methyl 3-(2-(thiophen-2-yl)acetamido)thiophene-2-carboxylate

SMILES COC(=O)c1sccc1NC(=O)Cc1cccs1

InChI Key InChIKey=CXOCENPNQSXLGZ-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50332040   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant ERK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332040(CHEMBL1288895 | methyl 3-(2-(thiophen-2-yl)acetami...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair