BDBM50332353 (3',4'-difluoro-4-(methylsulfonyl)biphenyl-2-yl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone::CHEMBL1631199

SMILES CS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2)c(c1)C(=O)N1Cc2cc(cnc2C1)C(F)(F)F

InChI Key InChIKey=HXKDSNZJKHAINQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332353   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50332353((3',4'-difluoro-4-(methylsulfonyl)biphenyl-2-yl)(3...)
Affinity DataEC50:  30nMAssay Description:Inhibition of human GlyT1 expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50332353((3',4'-difluoro-4-(methylsulfonyl)biphenyl-2-yl)(3...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human GlyT2 expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed