BDBM50332634 CHEMBL1630807::N-(4-Methoxyphenyl)-7-oxo-7,7a-dihydrocyclopropa[b]chromene-1a(1H)-carboxamide
SMILES COc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1
InChI Key InChIKey=PPETWINIGCTIHV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50332634
Affinity DataKi: 800nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.04E+4nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair