BDBM50333089 (R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo[15.3.1.04,9] henicosa-1(21),4(9),5,7,15,17,19-heptaen-12-yl)hexanoic acid hydroxyamide::CHEMBL1631915

SMILES COc1cc2COc3ccccc3NC(=O)[C@@H](CCCCCC(=O)NO)OC\C=C/c(c2)c1

InChI Key InChIKey=LMOIMHSPFQECJG-XBKFQHLESA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50333089   

TargetHistone deacetylase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  155nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  382nMAssay Description:Inhibition of human HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  97nMAssay Description:Inhibition of human HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  284nMAssay Description:Inhibition of human HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  302nMAssay Description:Inhibition of human HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  152nMAssay Description:Inhibition of human HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333089((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  206nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed