BDBM50333235 CHEMBL1645263::N1-(4-chloro-3-fluorophenyl)-N2-(1-cyclohexylpyrrolidin-3-yl)oxalamide

SMILES Fc1cc(NC(=O)C(=O)NC2CCN(C2)C2CCCCC2)ccc1Cl

InChI Key InChIKey=SLMIKXBCOQUWAI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333235   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333235(CHEMBL1645263 | N1-(4-chloro-3-fluorophenyl)-N2-(1...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to HIV1 YU2 gp120 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333235(CHEMBL1645263 | N1-(4-chloro-3-fluorophenyl)-N2-(1...)
Affinity DataIC50:  5.71E+4nMAssay Description:Inhibition of HIV1 YU2 gp120 binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed