BDBM50333467 2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-cyclopropylthiophene-3-carboxamide::CHEMBL1641800

SMILES CC(C)(C)c1cc(C(=O)NC2CC2)c(NC(=O)Nc2ccc3[nH]ncc3c2)s1

InChI Key InChIKey=CKEFKLKYCNGDMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333467   

TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333467(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-cyclopr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333467(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-cyclopr...)
Affinity DataIC50:  685nMAssay Description:Inhibition of S6K1 in ribosomal protein S6 by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed